Droits du patient
Menée par des professionnels de santé, la recherche clinique vise à améliorer les connaissances de la structure, de la biologie et du fonctionnement du corps humain et la compréhension du développement des maladies. Elle permet aussi de développer des techniques de diagnostic plus fiables ou plus précoces et des techniques de soins plus efficaces ou moins invasives.
Le but de la recherche clinique est donc de faire progresser les connaissances actuelles sur l’être humain.
Droit à une information claire, loyale, exhaustive
Durant toute la durée de la recherche clinique, le participant doit recevoir une information claire, loyale et appropriée. Cette information doit tenir compte du degré de compréhension du participant.
Droit à la confidentialité
Les données recueillies dans le cadre du projet de recherche sont protégées par le secret médical. De fait, seules les personnes habilitées ont accès à ces données.
Droit à l'anonymat
L’identité des participants doit rester confidentielle et ne doit donc pas être révélée.
Droit de retrait
Le participant à une étude clinique peut interrompre sa participation à tout moment sans avoir à se justifier.
Droit de refuser de participer
La personne sollicitée pour participer à un projet de recherche n’est pas obligée d’accepter et n’a pas de justification à donner. Sa prise en charge doit rester intacte en cas de refus. Elle signe alors un document attestant que la qualité de sa prise en charge médicale et de ses relations avec l'équipe soignante ne sera pas affectée par la décision de ne pas participer à l'essai.
Le “consentement éclairé” est obligatoire pour toute participation à un essai clinique.
Droit à l'accès, à la modification et à la suppression des données
Toutes les données collectées sont soumises aux dispositions de la CNIL (loi Informatique et Libertés).
Droit à la communication des résultats globaux de l'essai
S’ils en font la demande, les participants doivent recevoir les résultats globaux de l’essai clinique.
Assurance
Le promoteur d’une étude clinique a l'obligation de prendre une assurance permettant d'indemniser les préjudices éventuels liés à la participation au projet de recherche.
La non opposition voire le consentement sont recherchés préalablement à l'inclusion d'un patient dans une étude soutenant la recherche.
Par conséquent, en tant que patient, vous pouvez à tout moment, vous rapprocher du médecin qui vous suit ou de l'Unité de recherche clinique (URC) et de la Direction pour signaler votre souhait de ne pas être inclus.
Contactez-nous :
Certaines études, dites non-interventionnelles, ne nécessitent pas la signature du consentement écrit mais uniquement le recueil de l’accord oral du patient ou d’un proche ou encore le fait de pas manifester son refus.
Cette procédure est souvent appliquée dans les études rétrospectives visant à recueillir des données présentes dans les dossiers médicaux des patients. La non-opposition du patient à participer à l’étude sera spécifiée dans son dossier médical.
Pour un essai clinique, seuls les patients qui donnent leur consentement (ou ne s’y oppose pas en fonction du type d’essai) peuvent participer à un essai clinique : Il est donc impossible d'être inclus sans le savoir.
Ce consentement peut être retiré à tout moment sans justification et sans compromettre la qualité de votre prise en charge par l’équipe médicale.
Votre participation à un projet de recherche qui nécessite votre consentement ne sera effective qu’après lecture de la notice d’information expliquant les objectifs et le déroulement de l’étude et la signature d’un consentement de participation à l’essai clinique.
Une fois le consentement signé, vous êtes « inclus » dans l’essai clinique. Cette inclusion n’est pas définitive, vous pouvez décider d’arrêter l’étude à tout moment.
Avant de donner votre consentement pour participer à un projet de recherche clinique, vous devez avoir compris les explications données par l’investigateur.
N’hésitez pas à poser des questions.
Si vous ne comprenez pas certaines phrases, demandez des explications à l’investigateur ou à son équipe.
Une bonne compréhension de la note d’information est essentielle avant de décider de participer à l’essai.
La note d’information qui vous est remise doit reprendre toutes les informations données par l’investigateur, elle doit décrire les modalités du traitement, les bénéfices attendus, les risques encourus, le déroulement de l’essai afin que vous sachiez comment il va se dérouler. Vous pouvez vous y référer à n’importe quel moment, dès que vous avez une interrogation.
Pour toute question concernant la protection de vos données personnelles, vous pouvez vous adresser au Délégué à la Protection des Données (DPO) : dpo@ghtpdfr.fr
Je découvre les dernières études
| DOI | PMID | Auteur(s) | Titre | Revue | ISSN | Année | Catég. | Type |
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| 10.1007/s40120-022-00430-z | 36564664 | De Sèze, J ; Suchet, L ; Mekies, C ; Manchon, E ; Labauge, P ; Guennoc, AM & al | The Place of Immune Reconstitution Therapy in the Management of Relapsing Multiple Sclerosis in France: An Expert Consensus. | Neurol Ther | 2193-8253 | 2023 | C | Review |
| 10.1177/13524585221130934 | 36345839 | Vukusic, S ; Marignier, R ; Ciron, J ; Bourre, B ; Cohen, M ; Deschamps, R & al | Pregnancy and neuromyelitis optica spectrum disorders: 2022 recommendations from the French Multiple Sclerosis Society. | Mult Scler | 1477-0970 | 2023 | B | Review |
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| 10.1016/j.rehab.2022.101651 | 35240327 | Chan, B ; Salib, M ; Faggianelli, F ; Marque, P ; Cormier, C ; Gasq, D | Selection criteria for surgical correction of equinovarus foot in adults with brain damage: A systematic scoping review. | Ann Phys Rehabil Med | 1877-0665 | 2023 | A | Review |
| 10.1016/j.encep.2021.08.015 | 35012899 | Baltide, L ; Rolland, AC ; Eutrope, J ; Novo, A | [Crisis consultations in child and adolescent psychiatry in Reims: Cross-sectional study of the population of accompanied minors]. | Encephale | 0013-7006 | 2023 | D | Journal Article |
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| 10.3390/genes13122213 | 36553480 | Ben Aissa-Haj, J ; Pinheiro, H ; Cornelis, F ; Sebai, M ; Meseure, D ; Briaux, A & al | The Identification of Large Rearrangements Involving Intron 2 of the <i>CDH1</i> Gene in <i>BRCA1/2</i> Negative and Breast Cancer Susceptibility. | Genes (Basel) | 2073-4425 | 2022 | C | Journal Article |
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| 10.3389/fcvm.2022.951016 | 36158835 | Razazi, K ; Labbé, V ; Laine, L ; Bedet, A ; Carteaux, G ; de Prost, N & al | Hemodynamic effects and tolerance of dobutamine for myocardial dysfunction during septic shock: An observational multicenter prospective echocardiographic study. | Front Cardiovasc Med | 2297-055X | 2022 | C | Journal Article |
| 10.1186/s13613-022-01058-w | 36156744 | Egea, A ; Dupuis, C ; de Montmollin, E ; Wicky, PH ; Patrier, J ; Jaquet, P & al | Augmented renal clearance in the ICU: estimation, incidence, risk factors and consequences-a retrospective observational study. | Ann Intensive Care | 2110-5820 | 2022 | B | Journal Article |
| 10.3390/antibiotics11091166 | 36139946 | de Montmollin, E ; Peoc''''h, K ; Marzouk, M ; Ruckly, S ; Wicky, PH ; Patrier, J & al | Mid-Regional Pro-Adrenomedullin as a Prognostic Factor for Severe COVID-19 ARDS. | Antibiotics (Basel) | 2079-6382 | 2022 | B | Journal Article |
| 10.1016/j.jaut.2022.102908 | 36126365 | Azoulay, LD ; Pineton de Chambrun, M ; Larcher, R ; Pène, F ; Argaud, L ; Mayaux, J & al | Prevalence, characteristics and outcome of cardiac manifestations in critically-ill antiphospholipid syndrome patients. | J Autoimmun | 1095-9157 | 2022 | A | Journal Article |
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| 10.1136/jnnp-2021-327899 | 36008115 | Kachaner, A ; Lemogne, C ; Dave, J ; Ranque, B ; de Broucker, T ; Meppiel, E | <b>Somatic symptom disorder in patients with post-COVID-19 neurological symptoms: a preliminary report from the somatic study (Somatic Symptom Disorder Triggered by COVID-19</b>). | J Neurol Neurosurg Psychiatry | 1468-330X | 2022 | A | Journal Article |
| 10.3389/fphys.2022.918620 | 36003639 | Allegrini, B ; Jedele, S ; David Nguyen, L ; Mignotet, M ; Rapetti-Mauss, R ; Etchebest, C & al | New KCNN4 Variants Associated With Anemia: Stomatocytosis Without Erythrocyte Dehydration. | Front Physiol | 1664-042X | 2022 | B | Journal Article |
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| 10.1016/j.jogoh.2022.102459 | 35981706 | Tran, M ; Alessandrini, V ; Lepercq, J ; Goffinet, F | Risk of preeclampsia in patients with symptomatic COVID-19 infection. | J Gynecol Obstet Hum Reprod | 2468-7847 | 2022 | E | Journal Article |
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| 10.1186/s12887-022-03460-6 | 35840935 | Le Soudéer, L ; Truong, J ; Le Gal, J ; Escoda, S | Shigella-associated mild encephalitis with reversible splenial lesion in Hospital Center Delafontaine, Saint-Denis, France: a case report. | BMC Pediatr | 1471-2431 | 2022 | D | Journal Article |
| 10.1016/j.purol.2022.05.001 | 35729028 | Turmel, N ; Hentzen, C ; Tan, E ; Haddad, R ; Chesnel, C ; Le Breton, F & al | Aqua: A new questionnaire assessing anticholinergic side effects in neurogenic population (Aqua: Anticholinergic side effects questionnaire). | Prog Urol | 1166-7087 | 2022 | E | Journal Article |
| 10.1002/mds.29124 | 35708213 | Coku, I ; Mutez, E ; Eddarkaoui, S ; Carrier, S ; Marchand, A ; Deldycke, C & al | Functional Analyses of Two Novel LRRK2 Pathogenic Variants in Familial Parkinson''s Disease. | Mov Disord | 1531-8257 | 2022 | A | Journal Article |
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| 10.1007/s15010-022-01855-2 | 35657529 | Akroum, S ; Tubiana, S ; de Broucker, T ; Dournon, N ; Varon, E ; Ploy, MC & al | Long-term neuro-functional disability in adult patients with community-acquired bacterial meningitis. | Infection | 1439-0973 | 2022 | B | Journal Article |
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| 10.1186/s12874-022-01623-8 | 35637426 | Lefort, M ; Sharmin, S ; Andersen, JB ; Vukusic, S ; Casey, R ; Debouverie, M & al | Impact of methodological choices in comparative effectiveness studies: application in natalizumab versus fingolimod comparison among patients with multiple sclerosis. | BMC Med Res Methodol | 1471-2288 | 2022 | B | Journal Article |
| 10.1016/j.jpeds.2022.05.018 | 35577119 | Aubart, M ; Roux, CJ ; Durrleman, C ; Gins, C ; Hully, M ; Kossorotoff, M & al | Neuroinflammatory Disease following Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Children. | J Pediatr | 1097-6833 | 2022 | A | Journal Article |
| 10.1073/pnas.2200413119 | 35576468 | Manry, J ; Bastard, P ; Gervais, A ; Le Voyer, T ; Rosain, J ; Philippot, Q & al | The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies. | Proc Natl Acad Sci U S A | 1091-6490 | 2022 | B | Journal Article |
| 10.1016/j.jhin.2022.05.003 | 35569577 | Nagle, S ; Tandjaoui-Lambiotte, Y ; Boubaya, M ; Athenaïs, G ; Alloui, C ; Bloch-Queyrat, C & al | Environmental SARS-CoV-2 contamination in hospital rooms of patients with acute COVID-19. | J Hosp Infect | 1532-2939 | 2022 | A | Journal Article |
| 10.3389/fmicb.2022.863777 | 35531285 | d''''Humières, C ; Gaïa, N ; Gueye, S ; de Lastours, V ; Leflon-Guibout, V ; Maataoui, N & al | Contribution of Clinical Metagenomics to the Diagnosis of Bone and Joint Infections. | Front Microbiol | 1664-302X | 2022 | B | Journal Article |
| 10.1016/j.rbmo.2021.12.019 | 35525718 | Mangiardi-Veltin, M ; Sebbag, C ; Rousset-Jablonski, C ; Ray-Coquard, I ; Berkach, C ; Laot, L & al | Pregnancy, fertility concerns and fertility preservation procedures in a national study of French breast cancer survivors. | Reprod Biomed Online | 1472-6491 | 2022 | B | Journal Article |
| 10.1016/j.otsr.2022.103286 | 35470117 | El Ghazoui, A ; Haddaoui, J ; Zahar, EM ; Sekkach, N | Humeral shaft fracture: Outcomes of percutaneous antegrade intramedullary nailing using the long Telegraph® nail with dynamic distal locking. | Orthop Traumatol Surg Res | 1877-0568 | 2022 | D | Journal Article |
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| 10.5489/cuaj.7709 | 35426785 | Berradja, S ; Turmel, N ; Hentzen, C ; Haddad, R ; Miget, G ; Grasland, M & al | French version of the short form of the Neurogenic Bladder Symptom Score: Cross-cultural adaptation and validation. | Can Urol Assoc J | 1911-6470 | 2022 | D | Journal Article |
| 10.1038/s41467-022-29380-8 | 35379786 | Zayed, A ; Baranowski, C ; Compagnion, AC ; Vernochet, C ; Karaki, S ; Cuttoli, RD & al | SWI/SNF chromatin remodeler complex within the reward pathway is required for behavioral adaptations to stress. | Nat Commun | 2041-1723 | 2022 | A | Journal Article |
| 10.5588/ijtld.22.0033 | 35351232 | Tandjaoui-Lambiotte, Y ; Crockett, F ; Nunes, H ; Annesi-Maesano, I ; Sésé, L | Air pollution: the silent killer is also indoors. | Int J Tuberc Lung Dis | 1815-7920 | 2022 | D | Journal Article |
| 10.1016/j.eclinm.2022.101362 | 35350097 | Hermine, O ; Mariette, X ; Porcher, R ; Djossou, F ; Nguyen, Y ; Arlet, JB & al | Tocilizumab plus dexamethasone versus dexamethasone in patients with moderate-to-severe COVID-19 pneumonia: A randomised clinical trial from the CORIMUNO-19 study group. | EClinicalMedicine | 2589-5370 | 2022 | A | Journal Article |
| 10.1186/s13756-022-01084-0 | 35346373 | Contejean, A ; Abbara, S ; Chentouh, R ; Alviset, S ; Grignano, E ; Gastli, N & al | Antimicrobial stewardship in high-risk febrile neutropenia patients. | Antimicrob Resist Infect Control | 2047-2994 | 2022 | B | Journal Article |
| 10.1111/hsc.13797 | 35315551 | Roland, N ; Ahogbehossou, Y ; Hatem, G ; Yacini, L ; Feldmann, L ; Saurel-Cubizolles, MJ & al | Violence against women and perceived health: An observational survey of patients treated in the multidisciplinary structure ''The Women''s House'' and two Family Planning Centres in the metropolitan Paris area. | Health Soc Care Community | 1365-2524 | 2022 | C | Journal Article |
| 10.1016/j.clinre.2022.101900 | 35259498 | Desprez, C ; Turmel, N ; Chesnel, C ; Sheikh Ismael, S ; Tamiatto, M ; Tan, E & al | Fecal incontinence subtype assessment (FI-SA): A new tool to distinguish among subtypes of fecal incontinence in a neurogenic population. | Clin Res Hepatol Gastroenterol | 2210-741X | 2022 | D | Review |
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| 10.1007/s00234-022-02919-8 | 35199209 | Forestier, G ; Escalard, S ; Sedat, J ; Saleme, S ; Mounayer, C ; Montcuquet, A & al | Non-ischemic cerebral enhancing lesions after thrombectomy: a multicentric retrospective French national registry. | Neuroradiology | 1432-1920 | 2022 | D | Journal Article |
| 10.1093/rheumatology/keac107 | 35199139 | Dabbak, I ; Rodero, MP ; Aeschlimann, FA ; Authier, FJ ; Bodemer, C ; Quartier, P & al | Efficacy and tolerance of corticosteroids and methotrexate in patients with juvenile dermatomyositis: a retrospective cohort study. | Rheumatology (Oxford) | 1462-0332 | 2022 | B | Journal Article |
| 10.1097/CCM.0000000000005485 | 35167501 | de Montmollin, E ; Dupuis, C ; Jaquet, P ; Sarton, B ; Sazio, C ; Susset, V & al | Herpes Simplex Virus Encephalitis With Initial Negative Polymerase Chain Reaction in the Cerebrospinal Fluid: Prevalence, Associated Factors, and Clinical Impact. | Crit Care Med | 1530-0293 | 2022 | B | Journal Article |
| 10.1016/j.jcrc.2022.154003 | 35152141 | Bailleul, C ; Puymirat, E ; Aegerter, P ; Guidet, B ; Guerot, E ; Augy, JL & al | In-hospital cardiac arrests admitted alive in intensive care units: Insights from the CubRéa database. | J Crit Care | 1557-8615 | 2022 | C | Journal Article |
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